Efficacy and Safety of Long Term Brentuximab Vedotin Therapy and Retreatment in an AIDS Patient Affected by Refractory/Relapsed Anaplastic Large Cell Lymphoma: Case Report and Literature Review

نویسندگان

  • Alice Di Rocco
  • Federico De Angelis
  • Luigi Petrucci
چکیده

Lymphoma is the most common type of cancer in patients infected with HIV despite of the introduction of the antiretroviral therapy. Brentuximab Vedotin (BV) is an anti-CD30 antibody-drug conjugate, which has been approved for the treatment of relapsed or refractory Hodgkin lymphoma and anaplastic large cell lymphoma (ALCL). However, fewer data are available on the role of the BV in the treatment of HIV-CD30+ lymphomas and of its impact on outcomes. We describe the first case of retreatment with BV in a HIV patient with ALCL, ALKwho relapsed after a complete response to a previous BV treatment.

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تاریخ انتشار 2017